KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THOC2
All Species:
37.27
Human Site:
Y1090
Identified Species:
63.08
UniProt:
Q8NI27
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NI27
NP_001075019.1
1593
182775
Y1090
N
K
A
D
Q
L
D
Y
E
N
F
R
H
V
V
Chimpanzee
Pan troglodytes
XP_001139291
1595
183045
Y1092
N
K
A
D
Q
L
D
Y
E
N
F
R
H
V
V
Rhesus Macaque
Macaca mulatta
XP_001086217
1593
182783
Y1090
N
K
A
D
Q
L
D
Y
E
N
F
R
H
V
V
Dog
Lupus familis
XP_538164
1593
182721
Y1090
N
K
A
D
Q
L
D
Y
E
N
F
R
H
V
V
Cat
Felis silvestris
Mouse
Mus musculus
B1AZI6
1594
182755
Y1090
N
K
A
D
Q
L
D
Y
E
N
F
R
H
V
V
Rat
Rattus norvegicus
XP_233081
1594
182711
Y1090
N
K
A
D
Q
L
D
Y
E
N
F
R
H
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510761
1648
188085
Y1141
N
K
A
D
Q
L
D
Y
E
N
F
R
H
V
V
Chicken
Gallus gallus
XP_420332
1593
182430
Y1087
N
K
A
D
Q
L
D
Y
E
N
F
R
H
V
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001003847
1504
172218
P1049
E
K
E
C
G
N
Y
P
G
F
L
T
I
F
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722763
1641
188490
E1158
A
N
D
H
V
G
Y
E
N
Y
R
H
V
C
H
Honey Bee
Apis mellifera
XP_393587
1354
156054
S902
D
S
K
D
V
N
V
S
K
G
K
K
E
Q
E
Nematode Worm
Caenorhab. elegans
NP_498392
1437
164369
E946
K
K
D
S
L
I
D
E
Q
F
H
N
S
V
L
Sea Urchin
Strong. purpuratus
XP_795489
1592
178912
Y1086
N
K
A
D
Q
L
D
Y
E
N
F
R
H
V
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_173871
1804
205705
K1131
V
T
F
G
Q
F
V
K
V
H
W
K
W
S
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
99.9
99
N.A.
97.4
97.4
N.A.
85.8
88.1
N.A.
72.9
N.A.
39.7
43.1
29.5
48.7
Protein Similarity:
100
99.3
100
99.3
N.A.
98.9
99
N.A.
91.4
93.9
N.A.
83.4
N.A.
59
60.2
48.5
65.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
N.A.
6.6
N.A.
0
6.6
20
93.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
N.A.
6.6
N.A.
0
26.6
40
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
65
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
8
% C
% Asp:
8
0
15
72
0
0
72
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
8
0
0
0
0
15
65
0
0
0
8
0
8
% E
% Phe:
0
0
8
0
0
8
0
0
0
15
65
0
0
8
0
% F
% Gly:
0
0
0
8
8
8
0
0
8
8
0
0
0
0
8
% G
% His:
0
0
0
8
0
0
0
0
0
8
8
8
65
0
8
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% I
% Lys:
8
79
8
0
0
0
0
8
8
0
8
15
0
0
0
% K
% Leu:
0
0
0
0
8
65
0
0
0
0
8
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
65
8
0
0
0
15
0
0
8
65
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
72
0
0
0
8
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
65
0
0
8
% R
% Ser:
0
8
0
8
0
0
0
8
0
0
0
0
8
8
0
% S
% Thr:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% T
% Val:
8
0
0
0
15
0
15
0
8
0
0
0
8
72
58
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
15
65
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _